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Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1, mitigates interferon-alpha-accelerated lupus nephritis in mice

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Chronic conditions may benefit from extended treatment periods of 3-6 months, followed by maintenance dosing or cycling protocols

This highlights the potential treatment role of targeting the NLRP3 pathway in managing cardiac complications associated with dysbiosis and LPS-induced inflammation